Yes you can and some bowlers just use two fingers while bowling, they just don’t use their thumb. The are pros and cons juts by using two fingers. With the new rules from the PBA, every hole in the bowling ball must be used. So if you bowl with two fingers then you can only have two holes in the bowling ball. Some people can’t just with two fingers for bowlers and they need to use their thumb as well. It may be harder to roll the ball straighter just using two fingers. There are not a lot of pro bowlers that just use two fingers even with the people who bowl with two hands. Some of the pros of bowling with two fingers are you have more pin action, more power and hook with two fingers.